Postoperative pancreatic fistula formation (POPF) is the Achilles Heel of pancreatic surgery for hepatobiliary and upper GI surgeons¹. Clinical impact incidence remains high¹, and POPFs are associated with complications, hospital readmissions, and reoperations.
In a retrospective study of distal pancreatectomy patients, use of the AEON™ endoscopic surgical stapler was associated with a 69% relative reduction in postoperative pancreatic fistula (POPF) rate (20% vs. 65%, p = 0.001), significantly lower postoperative day 3 drain lipase levels (446 U/L vs. 4,208 U/L, p = 0.018), and a shorter mean hospital stay (6.2 vs. 8.7 days, p = 0.018).
“…this data can recommend that the AEON™ stapler with the Orange cartridge (Open Height 3.25 mm, Closed Height 1.5 mm) has a positive role to play in transection of the pancreas…”
“Notable difference in drain output and drain lipase measurements after switching to the AEON™ stapler were considered important to investigate and report especially as a reduction in the POPF rate is probably the single most important post-operative outcome measurement for distal or lateral pancreatectomy.”