New study finds AEON™ associated with 70% reduction in post-operative pancreatic fistula rate

Postoperative pancreatic fistula formation (POPF) is the Achilles Heel of pancreatic surgery for hepatobiliary and upper GI surgeons¹. Clinical impact incidence remains high¹, and POPFs are associated with complications, hospital readmissions, and reoperations.

In a retrospective study of distal pancreatectomy patients, use of the AEON™ endoscopic surgical stapler was associated with a 69% relative reduction in postoperative pancreatic fistula (POPF) rate (20% vs. 65%, p = 0.001), significantly lower postoperative day 3 drain lipase levels (446 U/L vs. 4,208 U/L, p = 0.018), and a shorter mean hospital stay (6.2 vs. 8.7 days, p = 0.018).

 

AEON stapler study done by Prof Aali Sheen with breakthrough results in HPB surgery surgical stapling

“…this data can recommend that the AEON™ stapler with the Orange cartridge (Open Height 3.25 mm, Closed Height 1.5 mm) has a positive role to play in transection of the pancreas…”

“Notable difference in drain output and drain lipase measurements after switching to the AEON™ stapler were considered important to investigate and report especially as a reduction in the POPF rate is probably the single most important post-operative outcome measurement for distal or lateral pancreatectomy.”

[1] Chikhladze, S., et al. “The rate of postoperative pancreatic fistula after distal pancreatectomy is independent of the pancreatic stump closure technique–A retrospective analysis of 284 cases.” Asian Journal of Surgery 43.1 (2020): 227-233.

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The AEON™ Powered Surgical Stapling System from Lexington Medical, Inc., showing the Powered Handle 2.0 (Medium) with a reload loaded alongside the AEON™ Control Unit in a top-angled view. The corded handle connects to the Controls, which powers the stapling handle and the calculations. Manufactured by Lexington Medical, Inc. No background.