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AEON™ Endoscopic Stapling System

Engineered for Trusted Precision, Seamless Control, and Surgical Efficiency

Breakthrough Engineering in Every Fire — S3 Engineering™

Multi-Speed Gear

The most innovative feature in the surgical stapling category. Like downshifting on a bicycle to pedal uphill, switching to AEON’s Thick Mode gear reduces firing force for improved staple formation and superior hemostasis in thick tissue.

Superior Staple Lines

In head-to-head randomized controlled trials versus leading legacy competitors, AEON™ saw less bleeding and drier staple lines. #footnotes [1][2]

Smooth Articulation

Precise stapler positioning with fluid range of motion.

AEON Endoscopic Surgical Stapler with S3 Engineering, angled reload and Made in USA sign
AEON Endoscopic Manual Surgical Stapler Multi-Speed Gear Close Up
Picture of top of AEON Endostapler showing turning handle for smooth articulation.
Hemostasis and aerostasis; superior staple lines with AEON in bariatric surgery

Precision You Can Feel

Patented Technologies That Transform Staple Lines

AEON Endoscopic Manual Surgical Stapler with Reload
Better staple formation in thick tissue
Advanced reload architecture
Stronger staple lines 
Smooth articulation
Multi-speed gear
Complete reload menu

Stronger Staple Lines Start with Smarter Reload Design

Delivering strong, hemostatic staple lines.

Picture of a Curved Tip AEON Reload.

Precise clean transections with single-use anvil and blade design

3 rows of protection with uniform staple height

Better staple formation and less tissue crushing with I-beam localized compression design

Designed for improved surgical access with narrow 6-row anvils

One Handle.
Every Reload.
Complete Surgical Versatility.

Each AEON™ handle is compatible with all AEON™ reloads. Use 30mm, 45mm, and 60mm reloads in a single surgery with a single handle.

The Most Comprehensive Staple Height Range

Widest menu of staple height offering

AEON™ provides surgeons unmatched versatility with 36 unique reload configurations designed for virtually any surgical need. Supporting tissue thicknesses from 0.75 mm to 4.0mm, AEON™ delivers the widest stapling range of any stapler brand—ensuring precise performance across thoracic, HPB, bariatric, colorectal, and general surgery applications.

[Internal Data on file]

Broadest selection of anvils

AEON™ provides surgeons with the optimal tool across a broad range of clinical applications, including the proprietary AEON™ short tip designed to reduce tissue trauma caused by stapler blunting.

Head-to-Head Proof:
AEON™ vs. Legacy Staplers in Published Trials

Proper B-formation rate by tissue thickness

Ex vivo porcine gastric tissue. 8 g/mm² compression.
AEON
Competitor

Testing performed with ex vivo porcine gastric tissue. Thickness measured at 8 g/mm² compression. Data on file (MC-021020).

Diagram comparing proper B-formation staples to malformed staple examples, with a table showing closed staple heights for AEON reloads vs competitors.

Frequently Asked Questions

AEON is an FDA-cleared endoscopic surgical stapling system designed and manufactured in the USA by Lexington Medical, Inc. (Bedford, MA). It is available in manual and powered versions and offers 36 reload configurations with the widest staple height range on the market.

Yes. A published clinical study found the AEON Endostapler produced a significantly drier staple line than the Echelon Flex Powered Stapler, reducing the need for additional bleeding-control interventions.

AEON’s Thick Mode gear reduces firing force in thick tissue, improving staple formation and hemostasis. AEON offers the widest staple height range on the market, covering tissue from fine vessels to thick stomach.

Unlock the Full Power of AEON™

Take AEON™ to its peak with our intelligent Powered Handle engineered for precision, comfort, and next‑level capability.

The AEON™ Powered Surgical Stapling System from Lexington Medical, Inc., showing the Powered Handle (Medium) with a reload loaded alongside the AEON™ Control Unit in a top-angled view.