Surgical Stapler Performance in Challenging Lung Tissue: Publication Video

What happens when stapler innovation doesn’t stand still?
A 2026 prospective randomized trial from University Hospital Basel compared the AEON Endostapler against the Echelon Flex Powered Plus in lung volume reduction surgery for patients with severe lung emphysema. Results showed an air leak incidence of 35.3% versus 60%, median closure time of 14.3 hours versus 93.2 hours, and total air leak volume at 32% of the powered comparator. This video presents the key clinical findings from Macharia-Nimietz et al., published in Interdisciplinary CardioVascular and Thoracic Surgery, 2026.
MIT MechE Students Explore Surgical Innovation at Lexington Medical, Inc.

Lexington Medical, Inc., a surgical stapling company based in Bedford, MA, recently welcomed MIT Mechanical Engineering students to our headquarters for an immersive experience in surgical innovation. The visit offered a behind-the-scenes look at how our team designs and builds smart surgical technology for minimally invasive procedures. Students toured our advanced manufacturing facility, where Lexington […]
Lexington Medical, Inc. Secures Growth Investment from Ampersand Capital Partners

Bedford, Massachusetts – PRNewswire Lexington Medical, Inc. (“Lexington”), a leader in minimally-invasive surgical stapling solutions, today announced a strategic investment by Ampersand Capital Partners (“Ampersand”), a private equity firm specializing in growth equity investments in the healthcare and life sciences sectors. The partnership underscores Ampersand’s confidence in Lexington’s potential to redefine surgical stapling standards and […]
Lexington: Built With Purpose | Our CEO Shares the Story
At Lexington Medical, Inc., we’re here to make the most critical tool in the OR — the surgical stapler — the best in the world. In this video, our CEO shares the story behind that mission: how we started, what drives us, and where we’re going. If you’re ready to build something exceptional, we’re hiring. […]
Groundbreaking Milestone: Lexington Medical, Inc. launches AEON™ Powered Stapling System

Lexington Medical, Inc. is thrilled to announce the FDA clearance and launch of the AEON™ Powered Stapling System, the most advanced next generation surgical stapling platform. The new stapling system is designed to deliver the most optimized stapling experience and outcomes with the industry-leading AEON™ specialized reload menu. “This represents a major step forward for […]
Professor Antanas Mickevičius discusses AEON™

Meet Professor Mickevičius, a dedicated surgeon committed to delivering the best outcomes for his patients, and learn why he trusts AEON™ for its exceptional quality and how our dynamic team at Lexington Medical, Inc. uses flexibility and agility to meet the evolving needs of healthcare professionals like him.
Responsibility. Choice. Service.

Lives depend on the quality of the staple line our product deploys. That is why we work hard every day to deliver the best staple line and the best clinical outcomes. We seek this responsibility because we wish to serve the surgeons who have dedicated themselves to their patients. We chose surgical stapling because we […]
New publication reveals superior clinical performance

A new publication reveals superior clinical performance and a statistically significant reduction in staple line bleeding when using AEON™ in Roux-en-Y gastric bypass procedures. Both AEON™ and leading competitor were found to be safe and effective with low complication rates and comparable clinical performance in sleeve gastrectomy and single anastomosis duodenoileostomy with gastric sleeve procedures. […]
Distal Pancreatectomy Study Publication Assessing Clinical Outcomes Using AEON™

New published study assessing clinical outcomes in distal pancreatectomy surgery finds AEON™ associated with significantly reduced pancreatic fistula leak rate, shortened hospital length-of stay, and noted reduction in drain fluid output. https://youtu.be/rngXmgqljUI
New study finds AEON™ associated with 70% reduction in post-operative pancreatic fistula rate

Postoperative pancreatic fistula formation (POPF) is the Achilles Heel of pancreatic surgery for hepatobiliary and upper GI surgeons¹. Clinical impact incidence remains high¹, and POPFs are associated with complications, hospital readmissions, and reoperations. In a retrospective study of distal pancreatectomy patients, use of the AEON™ endoscopic surgical stapler was associated with a 69% relative reduction […]